Lymphocytic choriomeningitis (LCM) is an infectious viral illness transmitted by rodents. This is caused by the lymphocytic choriomeningitis virus (LCMV), a member of the family Arenaviridae. The common house mouse is the virus’s major reservoir. Despite the fact that LCMV is known to cause neurological illness, infection without symptoms is quite prevalent. Other species of rodents, such as hamsters, are not natural reservoirs for LCMV, although they may be infected by wild mice at the pet shop, home setting, or breeder. Humans are more likely to catch LCMV from house mice, although infections have also been observed in rodents kept as pets.
Infections with LCMV have been documented in Japan, the Americas, Europe, and Australia and may occur anywhere infected rodent hosts exist. Historically, the condition has been underreported, making it difficult to derive incidence rates or prevalence estimates by geographic location.