Latanoprostene bunod is a synthetic counterpart of naturally occurring prostaglandin F2 that donates nitric oxide. It’s a prodrug that’s hypothesized to reduce intraocular pressure by increasing aqueous humor outflow via both the trabecular meshwork (traditional route mediated by nitric oxide) and the uveoscleral pathway (nontraditional route mediated by latanoprost acid).


Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist. 

Latanoprostene bunod is used in the following conditions:

  • Open-angle glaucoma
  • Ocular hypertension

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.  

Do not use Latanoprostene bunod in people with the following conditions:

  • Active intraocular inflammation

Latanoprostene bunod may have the following side effects:

  • Changes in the growth, length, thickness, quantity, and pigmentation of the eyelashes
  • Increased or changed pigmentation of the iris and eyelid skin
  • Intraocular inflammation
  • Cystoid macular edema
  • Keratitis caused by bacteria
  • Blurred vision
  • Punctate keratitis
  • Freign body sensation
  • Conjunctival hyperemia
  • Eye irritation or pain
  • Instillation site pain
  • Conjunctival oedema

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects. 

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Intraocular inflammation
  • Aphakia
  • Ruptured posterior lens capsule, which develops pseudophakia
  • Pregnancy
  • Lactation

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.


Latanoprostene bunod may interact with the following medicines:

  • Ophthalmic bimatoprost
  • Topical bimatoprost
  • Ophthalmic latanoprost
  • Ophthalmic tafluprost
  • Ophthalmic Travoprost
  • Ophthalmic unoprostone

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice. 

If you suspect an overdose, contact your health care practitioner right away.

Available Brands:

  • Vyzulta

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