LANSOPRAZOLE - Watsons Health

LANSOPRAZOLE

Lansoprazole is a drug that belongs to a class of medicines known as substituted benzimidazoles. It is also known as a proton pump inhibitor because it can block acid secretion by inhibiting H+/K+ ATPase enzyme system in gastric parietal cells. Both basal and stimulated acid are inhibited.

Lansoprazole is used in the following conditions:

  • Acid-related dyspepsia
  • Gastroesophageal reflux disease
  • Erosive oesophagitis
  • Peptic ulcer
  • H.pylori infection
  • NSAID-associated ulceration
  • Zollinger-Ellison syndrome

Lansoprazole should not be given concomitantly with rilpivirine and atazanavir.

Lansoprazole may have the following side effects:

  • Increased risk of Clostridium difficile-associated diarrhoea (CDAD)
  • Risk of osteoporosis-related fractures
  • Diarrhoea
  • Abdominal pain
  • Nausea
  • Vomiting
  • Flatulence
  • Constipation
  • Headache
  • Dry mouth
  • Peripheral oedema
  • Dizziness
  • Sleep disturbances
  • Fatigue
  • Paraesthesia
  • Arthralgia
  • Myalgia
  • Rash
  • Pruritus
  • Pancreatitis
  • Glossitis
  • Tremor
  • Anorexia
  • Restlessness
  • Impotence
  • Petechiae
  • Purpura
  • Taste disturbance
  • Stomatitis
  • Hepatitis
  • Jaundice
  • Hypersensitivity reactions (e.g. bronchospasm)
  • Fever
  • Depression
  • Hallucinations
  • Confusion
  • Gynaecomastia
  • Interstitial nephritis
  • Hyponatraemia
  • Hypomagnesaemia
  • Blood disorders (e.g. leucopenia, leucocytosis, pancytopenia, thrombocytopenia)
  • Visual disturbances
  • Sweating
  • Photosensitivity
  • Alopecia
  • Colitis
  • Increased serum cholesterol or triglyceride
  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis

Precautions

Lansoprazole should be used with caution in those with gastric cancer, liver problems, and those who are pregnant or breastfeeding.

 

Interactions

Lansoprazole may interact with the following medicines:

  • Diuretics
  • Digoxin
  • Erlotinib
  • Dasatinib
  • Lapatinib
  • Itraconazole
  • Ketoconazole
  • Cilostazol
  • Methotrexate
  • Antacids
  • Sucralfate
  • Rilpivirine
  • Atazanavir

If you think you may have taken lansoprazole more than the usual dosage, seek medical help immediately.

 

Available Brands:

  • Prevacid

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