LANREOTIDE

COMMON BRAND NAME(S): Somatuline

GENERIC NAME(S): LANREOTIDE

 

Description: Lanreotide is a somatostatin analogue which inhibits various endocrine, neuroendocrine, exocrine and paracrine functions such as the release of growth hormone by binding to human somatostatin receptors (SSTR2 and 5).

Pharmacokinetics:

Absorption: Absolute bioavailability: 50-80%.

Excretion: IV: 2.5 hr (terminal half-life).

This medication is a long-acting form of lanreotide. Lanreotide is used for long-term treatment of acromegaly. It is also used when surgery or radiation treatment have not been fully successful or cannot be used. Lanreotide works by decreasing the amount of growth hormone to normal levels. This medication is also used to treat certain cancer or tumors of the stomach, intestines, or pancreas by slowing down the growth of these tumors.

How to use lanreotide subcutaneous

Read the Patient Information Leaflet provided by your doctor or pharmacist before you start using lanreotide and before each monthly injection since there may be new information. If you have any questions, consult your doctor or pharmacist.

This medication is given by injection deep under the skin of your buttock by a health care professional, usually once every 4 weeks or as directed by your doctor. To reduce irritation from the injection, your doctor will alternate between the left and right buttock with each dose. Dosage is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. It may help to mark your calendar with a reminder (e.g., every 4 weeks).

Tell your doctor if your condition does not improve or if it worsens.

  • Allergic reaction from this medication
  • Patients with medical history of:

 

  • kidney disease
  • liver disease
  • diabetes
  • heart problems (e.g., slow heartbeat, high blood pressure, heart valve problems)
  • thyroid problems
  • gallbladder problems (e.g., gallstones)

 

  • This may make you dizzy
  • During pregnancy, this should be used only when clearly needed
  • unknown if this drug passes into breast milk

 

Consult your doctor or pharmacist regarding the precautions and warning mentioned above.

  • Tell your doctor or pharmacist promptly if any of these effects persist or worsen:
    • Headache
    • muscle/joint pain
    • dizziness
    • nausea
    • vomiting
    • loose stools
    • diarrhea
    • constipation
    • stomach upset
    • gas
    • weight loss
    • pain and irritation at the injection site

    Tell your doctor right away if you have any serious side effects, including:

    • signs of gallbladder problems/gallstones (e.g., fever, stomach/abdominal pain, severe nausea/vomiting, yellowing eyes/skin, unexplained pain in the back/right shoulder)
    • signs of an underactive thyroid (e.g., unexplained weight gain, cold intolerance, severe constipation, unusual/extreme tiredness, growth/lump/swelling on the front of the neck)
    • slow heartbeat
    • mental/mood changes (e.g., depression).

    This medication may infrequently cause changes in blood sugar (either increase or decrease), especially if you have diabetes. Tell your doctor if you experience any symptoms of such changes in blood sugar.

    This medication may raise your blood pressure.

    Get medical help right away if you notice any symptoms of a very rare but serious allergic reaction.

    This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

  • Beta blockers (e.g., metoprolol, propranolol), cyclosporine, and pegvisomant may interact with this drug.

If overdose is suspected, contact a poison control center or emergency room immediately.

Notes

Laboratory and/or medical tests (e.g., growth hormone levels, blood glucose tests, thyroid function tests, blood pressure, heart rate) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Missed Dose

For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule.

Storage

Not applicable. This medication is given in a clinic and will not be stored at home.

 

Brands

( Not Available )

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