ISOLEUCINE 33 AMYLOIDOSIS

Overview and Facts

Isoleucine 33 amyloidosis is an uncommon condition that develops when your organs accumulate an abnormal protein known as amyloid that ramps up in your organs and obstructs their functional capacity. Even though the body doesn’t generally contain amyloid, it can be created from a variety of protein kinds. The digestive system, neurological system, kidneys, liver, heart, spleen, and kidneys are some of the organs that could be impacted.

Some types of amyloidosis co-occur with other conditions. Treatment for the underlying illness may help. Life-threatening organ dysfunction can result from some types of amyloidosis. Chemotherapy used to fight cancer may be part of the therapy. To limit amyloid development and manage symptoms, your physician may recommend medication. Stem cell or organ transplants might be helpful for some persons.

Types and Symptoms

SYMPTOMS

Isoleucine 33 amyloidosis signs might not appear until the disease has progressed significantly. Depending on which of your organs is harmed, symptoms will become apparent.

Isoleucine 33 amyloidosis symptoms and signs may include:

  • Extreme weakness and weariness
  • Swelling of your legs and ankles
  • Shortness of breath
  • Tingling, numbness, pain in your feet, hands, and wrist
  • Sudden weight loss
  • Diarrhea
  • Skin changes
  • Enlarged tongue
  • Problems swallowing

Diagnosis & Medications

DIAGNOSIS

Isoleucine 33 amyloidosis is frequently disregarded since the signs and symptoms can resemble those of more widespread illnesses. Additional organ damage can be avoided with early detection. Because the type of treatment you receive depends heavily on your particular condition, a precise diagnosis is crucial.

Imaging tests

The extent of your condition can be determined using images of the amyloidosis-affected organs. These tests may include:

  • MRI
  • ECG
  • Nuclear imaging
  • Laboratory tests
  • Biopsy

Biopsy

It is possible to examine a tissue sample for evidence of amyloidosis. The biopsy can come from the bone marrow, the fat under your skin on your abdomen (fat aspirate), or an organ that is afflicted, like your liver or kidney.

Laboratory tests

Analyses of the aberrant proteins in your blood and urine may reveal amyloidosis.

TREATMENT

Isoleucine 33 amyloidosis has no known treatment. Therapy, however, can help control the signs and amyloid protein formation. Addressing the underlying disease may be useful if the amyloidosis was caused by another illness, including tuberculosis or rheumatoid arthritis.

Medications

  • Heart medications
  • Chemotherapy
  • Targeted therapies

Surgical and other methods

  • Organ transplant
  • Dialysis
  • Autologous blood stem cell transplant

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