Isocyanates are a class of low-molecular-weight, highly reactive compounds. They are employed in a wide variety of industrial items, such as paints, adhesives, and resins. Exposure to isocyanates is linked to several additional harmful health effects, including cancer as well as asthma and allergic contact dermatitis. Workers’ exposures must be carefully managed in situations where isocyanates are used or accidentally produced, such as when polyurethanes are heated.
The mucous membranes of the ocular, gastrointestinal, and respiratory systems are all severely irritated by isocyanates. Intense inflammation can also be brought on by direct skin contact. Additionally, exposure to isocyanates might sensitize employees, leaving them vulnerable to severe asthma episodes in the future. There is proof that sensitization can result from both cutaneous and inhalation exposures. There have been reports of some sensitive individuals passing away from acute asthma.