Infantile colic is a harmless condition wherein a baby has paroxysms of inconsolable weeping for more than three hours every day, three days every week, and for more than three weeks. It affects 10% to 40% of newborns globally, peaks at roughly six weeks, and resolves by three to six months of age. The incidence is the same for both sexes, and there is no association with socioeconomic position, gestational age, and feeding method.
Furthermore, the cause of infantile colic is unknown, but possible explanations include changes in nicotine replacement therapy or maternal smoking, poor feeding technique, increased serotonin secretion, inflammation or gastrointestinal immaturity, intolerance to lactose or milk protein, and fecal microflora.