IMBRUVICA

Do not use Imbruvica in people with the following conditions:

• Known hypersensitivity to ibrutinib or any components of the formulation
• Pregnant women

Imbruvica may have the following side effects:

• Fatigue, diarrhea, nausea, musculoskeletal pain, bruising, rash, anemia, and decreased appetite
• Other less common side effects may include: heartburn, difficulty sleeping, constipation, vomiting, muscle spasms, headache, dizziness, hair loss, and fever
• In rare cases, ibrutinib can cause severe and life-threatening side effects, such as bleeding, infection, heart problems, and liver problems

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

• Patients taking ibrutinib should not donate blood or plasma during treatment or for at least 1 month after stopping treatment
• Patients should also avoid activities that could cause a significant injury, as ibrutinib may increase the risk of bleeding
• It is important to be monitored for infection, as ibrutinib can increase the risk of infection

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Imbruvica may interact with the following medicines:

• Warfarin, antacids, and certain antibiotics. Warfarin is a blood thinner, and taking it with ibrutinib can increase the risk of bleeding
• Antacids can also affect the way ibrutinib is absorbed in the body, and certain antibiotics can interact with ibrutinib and cause a decrease in its effectiveness

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you suspect an overdose, contact your doctor right away.

Available Brands:

• Imbruvica