IDOXURIDINE

Idoxuridine is a drug that belongs to a class of medicines known as pyrimidine nucleosides. This drug is structurally similar to thymidine and is effective against viral infections. It stops viral replication by substituting itself for thymidine in the DNA of viruses. It is used to treat herpes simples and varicella zoster virus infections. It is effective against vaccinia virus, cytomegalovirus and adenovirus. It is usually applied to the skin and to the eyes as a solution.

Idoxuridine is used in the treatment of herpes simplex keratitis of the eyes and herpes simplex and herpes zoster infection of the skin.

Do not use Idoxuridine in people who are allergic to it.

Idoxuridine may bring about side effects such as the following:

  • Eye irritation
  • Inflammation of the eye or eyelids
  • Pain
  • Photophobia
  • Eye itching
  • Conjunctivitis
  • Eye swelling
  • Eye lachrymal duct occlusion
  • Eye hypersensitivity reactions
  • Corneal damage (prolonged use)
  • Skin irritation
  • Skin stinging
  • Skin hypersensitivity reactions
  • Corneal punctate defects

Skin maceration (when applied excessively)

Precautions

Extra caution should by people with the following medical conditions:

  • Deep ulceration of the stromal layers of the cornea of the eyes
  • Pregnancy
  • Breastfeeding

Do not use for long periods of time.

 

Interactions

Idoxuridine may interact with corticosteroids.

If you think you have used Idoxuridine for more than the recommended dose, seek medical help.

 

Available Brand/s:

  • Dendrid
  • Herpid
  • Herpidu
  • Idulea
  • Idustatin
  • Keresid
  • Oftan IDU
  • Virexen

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