GONADORELIN

COMMON BRAND NAME(S):

GENERIC NAME(S): GONADORELIN ACETATE

 

Description: Gonadorelin, a synthetic form of hypothalamic gonadotrophin-releasing hormone stimulates the synthesis and release of follicle-stimulating hormone and luteinizing hormone.

Gonadorelin is used by women who are missing menstrual periods by providing gonadotropin-releasing hormone (GnRH) which promotes ovulation. It may be used as part of female infertility treatment.

How to use gonadorelin injection

Read the Patient Information Leaflet if available from your pharmacist before you start using gonadorelin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Gonadorelin is injected into a vein or under the skin using an infusion pump, as directed by your doctor. If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the medication package. Follow all instructions for using the infusion pump. Do not mix this medication until you are ready to use it. Before using this medication, check the solution visually for particles or discoloration. If either is present, do not use the solution.

Before each dose, clean the injection site with rubbing alcohol. If you are injecting the medication under the skin, change the injection site as directed by your doctor to lessen injury under the skin. If you are injecting the medication into a vein, you do not need to change the injection site unless directed by your doctor.

The dosage is based on your medical condition and response to treatment. Keep all medical appointments so your doctor can closely monitor your response and adjust your dosage if necessary. Do not change the dose unless directed by your doctor, and do not use this medication for a longer period than prescribed.

Learn how to store and discard medical supplies safely.

Tell your doctor if your condition does not improve.

This medication may rarely cause a condition known as ovarian hyperstimulation syndrome (OHSS).

Tell your doctor right away if you have any serious side effects, including:

  • mental/mood changes (such as depression, agitation)
  • signs of infection (such as fever, chills, persistent redness/pain/swelling/warmth at the injection site)

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before using gonadorelin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: ovarian cysts, kidney disease, tumors of the pituitary gland (such as prolactinoma), cancer of the reproductive organs (such as ovary, breast, uterus).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Use of gonadorelin may cause multiple births (such as twins, triplets).

This medication may be used during the first trimester of pregnancy as directed by your doctor. Tell your doctor immediately if you become pregnant or think you may be pregnant. Consult your doctor for more details.

It is unknown if gonadorelin passes into breast milk. This medication is usually not used by nursing women. Consult your doctor before breast-feeding.

 

Interactions

Some other medications that cause ovulation may interact with this drug.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately.

Notes

Do not share this medication with others.

Laboratory and medical tests (such as blood hormone levels for estradiol/progesterone, ultrasounds) should be performed periodically to monitor your progress or check for side effects. Your doctor may ask you to monitor your body temperature. Consult your doctor for more details.

Missed Dose

For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

 

Brands

There are no brands containing this molecule.

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