GLYCINE

Other Names:

Acide Aminoacétique, Acide Amino-Acétique, Aminoacetic Acid, Athenon, Free Base Glycine, G Salt, Glicina, Glycine de Base Libre, Glycocoll, Glycosthene, Iconyl, L-Glycine, Monazol.

  • Treatment of schizophrenia, stroke, benign prostatic hyperplasia (BPH), and some rare inherited metabolic disorders
  • Also used to protect kidneys from the harmful side effects of certain drugs used after organ transplantation as well as the liver from harmful effects of alcohol, cancer prevention, memory enhancement, leg ulcers and wound healing

Minor side effects (if these symptoms persist or worsen, inform your doctor)

    • nausea
    • vomiting
    • stomach upset
    • and drowsiness.

Precautions

Inform your doctor:

    • Allergy to the medication or any allergies
    • If you are planning to be pregnant or think you may be pregnant, discuss the risks and benefits of use with your doctor.
    • It is uknown if this drug passes into breast milk. Before breast-feeding, consult your physician.

 

Interactions

Taking multiple drugs may affect how medications work and/or cause unwanted side effects. List down all the medications you are taking and inform your physician and pharmacist. Do not take, discontinue, or alter any dose of medications without prior approval of your physician.

  • Products that may interact with this medication include:
    • Clozapine (Clozaril)

The following doses have been studied in scientific research:

BY MOUTH:

For treating schizophrenia: Glycine has been used in doses ranging from 0.4 to 0.8 g/kg daily in divided doses. It is usually started at 4 g daily and increased by 4 g per day until the effective dose is reached.

UNDER THE TONGUE:

For protecting brain cells (neuroprotection) after onset on a stroke caused by a clot (ischemic stroke): 1 to 2 g per day started within 6 hours after stroke onset.

APPLIED TO THE SKIN:

For treating leg ulcers: A cream containing 10 mg of glycine, 2 mg of L-cysteine, and 1 mg of DL-threonine per gram of cream has been used. The cream was applied at each wound cleaning and dressing change once daily, every other day, or twice daily.

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