Gestodene is a drug that belongs to a class of medicines known as progestogens. This drug is similar in structure to Levonorgestrel. It is being used for contraception and hormonal replacement therapy.

Gestodene is used as an oral contraceptive along with other medicines. It is also used as hormone replacement treatment during menopause in women.

Gestodene should not be used by people with the following conditions:

  • Porphyria or bleeding disorders
  • Undiagnosed vaginal bleeding
  • History or current high risk of arterial disease
  • Severe liver impairment

Gestodene may give rise to side effects such as the following:

  • Gastrointestinal disturbances
  • Changes in appetite or weight
  • Swelling, fluid retention or edema
  • Acne
  • Chloasma (melasma)
  • Allergic skin rashes
  • Urticaria
  • Mental depression
  • Breast changes including discomfort or occasionally gynaecomastia
  • Changes in libido
  • Hair loss
  • Hirsutism
  • Fatigue
  • Drowsiness or insomnia
  • Fever
  • Headache
  • Premenstrual syndrome-like symptoms
  • Altered menstrual cycles
  • Anaphylaxis


Extra precaution should be observed with the following conditions:

  • Heart problems
  • Kidney problems
  • Asthma
  • Epilepsy
  • Migraine
  • Fluid retention
  • History of depression
  • High risk for thromboembolism
  • Diabetes



Gestodene may interact with the following medicines:

  • Felbamate
  • Carbamazepine
  • Griseofulvin
  • Phenobarbital
  • Phenytoin
  • Rifampicin
  • Ciclosporin

If you think you may have consumed more than the recommended dose, seek medical help immediately.


Available Brand/s:

Gynera, Meliane, Sophia

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