Gangrene is a local death of soft tissue due to decrease or lack of blood flow. It happens when tissues are not getting enough blood or not responding to your circulatory system. It usually happens in the farthest or most remote part of your body parts which may include the toes, fingers, and limbs. Aside from this, you can also get it in the muscles and organs. In some cases, this can causes sepsis in your body and can cause you to go into shock if not treated. This condition can bring about various symptoms such as low blood pressure, which can be life-threatening.