FERRIC CARBOXYMALTOSE

Ferric carboxymaltose is a colloidal iron (III) hydroxide complexed with a carbohydrate polymer that releases Fe required for myoglobin, Hb, and specific enzyme systems to operate. It is a stable non-dextran Fe formulation that enables the reticuloendothelial system to absorb Fe without releasing free Fe.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Uses

Ferric carboxymaltose is used in the following conditions:

Iron-deficiency anemia

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Ferric carboxymaltose in people with the following conditions:
- Fe overload, which causes hepatic impairment
- Excess of Fe or Fe utilization disturbances
- Microcytic anemia

Side Effects

Ferric carboxymaltose may have the following side effects:

Symptomatic hypophosphatemia
Tachycardia
Nausea
Dysgeusia
Abdominal pain
Diarrhea
Pyrexia
Chills
Angioedema
Back pain
Pain in extremity
Headache
Dyspnea
Rash
Urticaria
Hypotension

Kounis syndrome
Hypertension
Chest discomfort
Vomiting
Dyspepsia
Constipation
Injection or infusion site reactions
Fatigue
Edema peripheral
Myalgia
Arthralgia
Dizziness
Paraesthesia
Pruritus
Erythema
Flushing
Syncope

Potentially Fatal

Serious hypersensitivity reactions

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

History or existing of severe asthma
Atopic allergies
Acute or chronic infection
Hepatic or renal impairment
Lactation
Patients with a history of allergies
Eczema

Rheumatoid arthritis
Hypophosphatemia risk factors
Pregnancy (2nd-3rd trimester)

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Ferric carboxymaltose may interact with the following medicines:

Decreases oral Fe absorption; avoid starting oral treatment for at least 5 days after the previous IV Fe administration.

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

Symptoms of overdose may include the following:

Fe accumulation in storage areas that may result in hemosiderosis

Seek medical help immediately.

Available Brands:

Ferinject