FAMPISEC

Fampisec (Rifampicin) binds to the β subunit of DNA-dependent RNA polymerase, leading to inhibition of bacterial RNA synthesis.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully. 

Your physician’s medication dose is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages. 

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. Take it at a fixed time every day to make you remember it better. 

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions. 

If you have any inquiries regarding information, ask your physician or pharmacist.

Fampisec is used in the following conditions:

  • Prophylaxis against meningitis due to Haemophilus influenzae
  • Brucellosis, Legionnaires disease, Severe staphylococcal infections
  • Prevention of meningococcal meningitis
  • Leprosy
  • Tuberculosis

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information. 

Do not use Fampisec in people with the following conditions:

  • Hypersensitivity to rifampicin or other rifamycins
  • Jaundice

Fampisec may have the following side effects:

  • Generalised numbness
  • Fever
  • Thrombocytopenia
  • Discolouration
  • Fatigue
  • Pyrexia
  • Dizziness
  • Vomiting
  • Elevated liver enzymes
  • Urticaria
  • Behavioural changes
  • Nausea
  • Acute generalized exanthematous pustulosis
  • Facial or peripheral oedema
  • Toxic epidermal necrolysis
  • Visual disturbances
  • Increased blood bilirubin
  • Superinfection
  • Flu-like syndrome
  • Inability to concentrate
  • Anemia
  • Hyperbilirubinemia
  • Fulminant liver failure
  • Stevens-Johnson syndrome
  • AST
  • ALT
  • Muscle weakness
  • Drug reaction with eosinophilia and systemic symptoms (DRESS)
  • Angioedema
  • Chills
  • Rash
  • Menstrual disturbances
  • Jaundice
  • Leucopenia
  • Hepatitis
  • Headache
  • Drowsiness
  • Mental confusion
  • Pain in extremities

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.  

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling of the face or tongue or throat, dizziness or difficulty breathing. 

This is not a complete list of side effects. Contact your physician or pharmacist if you see other effects not recorded above.

Take extra caution in patients with the following medical conditions:

  • Chronic liver disease
  • Elderly
  • Poor nutritional status
  • Diabetes mellitus
  • Pregnancy
  • Renal and hepatic impairment
  • Children
  • Lactation
  • Patient with current or history of alcoholism
  • Receiving prolonged antibacterial or anticoagulant therapy
  • Porphyria

Before taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavourable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Fampisec may interact with the following medicines:

  • Hepatitis C antiviral drugs
  • Hormone antagonist
  • Antiarrhythmics
  • Antiepileptics
  • Antifungals
  • Beta-blockers
  • Isoniazid
  • Halothane
  • Antiretrovirals
  • Ca channel blocker
  • Antipsychotics
  • praziquantel
  • Anxiolytics and hypnotics
  • Cefazolin
  • Barbiturates
  • Anticoagulants

Inform your physician about the drugs you take, including over-the-counter medications, prescribed drugs, supplements and vitamins. 

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details. 

The effects of certain medications can change if you simultaneously consume different medications or herbal products. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking. 

While utilizing this drug, don’t start, stop, or change the dose of other medicines you use without your physician’s advice.

Symptoms of overdose may include the following: 

  • Nausea
  • Cardiac arrest
  • Facial or periorbital oedema (particularly in children)
  • Unconsciousness (in presence of severe hepatic disease)
  • Transient increases in liver enzymes
  • Liver enlargement
  • Lethargy
  • Pruritus
  • Abdominal pain
  • Seizures
  • Vomiting
  • Brownish-red or orange discolouration of the skin or urine
  • Ventricular arrhythmias
  • Hypotension
  • Headache
  • Bilirubin
  • Sinus tachycardia

Seek medical help immediately. 

Available Brands:

  • Rifadin
  • Natricin Forte
  • Picinaf
  • Rexilan
  • Kidz Kit 2/Kidz Kit 3
  • Rifadril

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