The most commonly used process in separating or isolating the red blood cells is a method called centrifugation. In this process, the whole blood is spun around in a centrifuge bowl, and its bottom part is where the red blood cells or erythrocytes will start to gather. These are then isolated, and the rest of the blood can be returned to circulation.
Centrifugation is commonly used because the volume of erythrocytes has the highest percentage over all the constituents of blood. Since red blood cells have the highest exact weight compared to other solid substances in the blood, it can be easily isolated with centrifugation.
Centrifugal sedimentation is the most popular method when it comes to the medical process of erythrocytapheresis. With this method, the donor or patient’s blood is gathered and prepared into a concentrate of erythrocytes that contain a high measure of hematocrit. This depleted, pre-sifted blood is gathered in an appropriate supply and siphoned into a centrifuge machine. The radial power will isolate the red blood cells from the blood’s other components because of their high explicit weight. These cells would then be ready to be gathered. Another step will prompt the expulsion of plasma parts, which will filter and concentrate the red blood cells. At that point, the rest of the blood will be transfused once again into the blood donor or patient.
The progression of centrifugation and layer filtration techniques is fundamental to the improvement of erythrocytapheresis. Moreover, the method of isolating blood on devices containing slender channels has been distinguished as a potentially applicable separation technique for red blood cells. Other erythrocyte and plasma isolation procedures are currently being investigated.