Ertugliflozin is a dominant, specific, and transient blocker of sodium-glucose co-transporter 2 (SGLT2), the major carrier in the kidney’s adjacent complex tubules accountable for processed glucose reuptake. Suppressing SGLT2 lowers the barrier for glucose in the kidneys and stops the kidneys from reabsorbing processed glucose. This makes more glucose leave the body through urine and lowers blood sugar levels.
Sitagliptin works by suppressing the protein dipeptidyl peptidase-4 (DPP-4) and leading to increased quantities of functional internal secretion. Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are internal secretion phytohormones that control glycemic control by boosting adrenaline production and secretion from peripheral cells while decreasing glucagon production. Reduced glucagon secretion results to a decrease in the production of hepatic glucose.
Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.
The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.
If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.
Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.
If you have any inquiries with regards to information, ask your physician or pharmacist.
