Ephedrine is a decongestant that works by reducing swelling in the nasal passages by constricting the blood vessels in the nose. It also serves as a bronchodilator by widening the lung airways for better breathing. Guaifenesin is an expectorant that helps loosen congestion in the chest and throat. It works by making it easier to cough out through your mouth.

Ephedrine-Guaifenesin is used to relieve congestion, cough, and throat and airway irritation that can be caused by colds, flu, or hay fever. This medication may also be used in other conditions to be determined by your doctor.

Do not use this medication if:

  • You are allergic to any ingredient in Ephedrine-Guaifenesin or if you have any allergies.
  • You have certain medical condition such as:
    • Severe High Blood Pressure
    • Rapid Heartbeat
    • Severe Heart Problems like Heart Blood Vessel Disease
  • You are using or have taken Furazolidone or a Monoamine Oxidase (MAO) Inhibitor (eg, Phenelzine) within the last 14 days

Common side effects of this drug may include:

  • Dizziness
  • Excitability
  • Headache
  • Nausea
  • Nervousness or Anxiety
  • Trouble Sleeping
  • Weakness

Notify your doctor promptly if any of these symptoms persist or worsen.

Severe side effects may include:

  • Severe Allergic Reactions (Rash; Hives; Swelling of the Mouth, Face, Lips, or Tongue)
  • Difficulty Urinating
  • Fast Or Irregular Heartbeat
  • Hallucinations
  • Seizures
  • Severe Dizziness
  • Lightheadedness
  • Headache
  • Tremor

Seek immediate medical attention if you experience any of these serious side effects.


Before using this combination medication, tell your doctor or pharmacist:

  • If you have allergies to medicines, foods, or other substances. Especially to the contents of this drug.
  • Your medical condition or medical history, especially of:
    • Adrenal Gland Problems (eg, Tumor)
    • Heart Problems
    • High Blood Pressure
    • Diabetes
    • Heart Blood Vessel Problems
    • Stroke
    • Glaucoma
    • An Enlarged Prostate or other Prostate Problems
    • Seizures
    • Overactive Thyroid
    • Fast, Slow, or Irregular Heartbeat
    • Chronic Cough
  • If you are pregnant, planning to become pregnant, or are breast-feeding
  • If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement



Drug interactions may either lessen the effectiveness of this drug or heighten the risk for severe side effects. It’s important to inform your doctor all the medication including prescription and non-prescription and herbal medicines you are taking or going to take.

Possible interactions with this drug are:

  • Beta-Blockers (eg, Propranolol)
  • Catechol-O-Methyltransferase (COMT) Inhibitors (eg, Tolcapone)
  • Furazolidone
  • Indomethacin
  • MAO Inhibitors (eg, Phenelzine)
  • Tricyclic Antidepressants (eg, Amitriptyline)
  • Digoxin or Droxidopa
  • Bromocriptine
  • Guanethidine
  • Guanadrel
  • Mecamylamine
  • Methyldopa

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Symptoms if overdose may include:

  • Blurred Vision
  • Confusion
  • Hallucinations
  • Seizures
  • Severe Dizziness
  • Lightheadedness or Headache
  • Severe Drowsiness
  • Unusually Fast, Slow, or Irregular Heartbeat
  • Vomiting


Available brand/s:

  • Altussan
  • Asmalex
  • Asvent Plus
  • Bronchospec
  • Colvan

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