ENOXACIN

Generic Name: enoxacin (ee NOX ah sin)

Brand Name: Penetrex

 

Description: Enoxacin inhibits DNA gyrase and topoisomerase IV which are essential in bacterial DNA reproduction.

Enoxacin, a fluoroquinolone antibiotic, treats various bacterial infections, such as gonorrhea and urinary tract infections. It may also be used for purposes other than those listed in this medication guide.

How to use Enoxacin:

Take enoxacin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take enoxacin with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent enoxacin crystals from forming in your urine.

Take enoxacin on an empty stomach 1 hour before or 2 hours after meals.

Take enoxacin at evenly spaced intervals. It is usually taken twice daily. Follow your doctor’s instructions.

Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 8 hours before or 2 hours after a dose of enoxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of enoxacin can greatly decrease the effects of the antibiotic.

Take all of the enoxacin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

Store this medication at room temperature away from moisture and heat.

Not available.

If you experience any of the following serious side effects, stop taking enoxacin and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives)
  • seizures
  • confusion or hallucinations
  • liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue)
  • muscle or joint pain

If you experience any of the following less serious side effects, continue taking enoxacin and talk to your doctor:

  • nausea
  • vomiting
  • diarrhea
  • headache
  • lightheadedness
  • drowsiness
  • ringing in your ears
  • increased sensitivity of the skin to sunlight

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Precautions

Take all of the enoxacin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

Drink plenty of extra fluids every day while taking enoxacin.

Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 8 hours before or 2 hours after a dose of enoxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of enoxacin can greatly decrease the effects of the antibiotic.

Interactions

Enoxacin and multivitamin with minerals should not be taken orally at the same time.

Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of enoxacin and reduce its effectiveness.

Using caffeine together with enoxacin may increase the effects of caffeine.

Severe Interactions of enoxacin: These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED PHOTOSENSITIZERS/TRETINOIN-MEQUINOL
  • ORAL QUINOLONES/STRONTIUM GLUCONATE AND RANELATE
  • ANTIBIOTICS/LIVE TYPHOID VACCINE
  • STRONG CYP1A2 INHIBITORS/TASIMELTEON
  • SELECTED FLUOROQUINOLONES/TIZANIDINE
  • POTENT CYP1A2 INHIBITORS/DULOXETINE
  • QUINOLONES/SELECTED ANTICOAGULANTS
  • QUINOLONES/THEOPHYLLINES

Overdose

Seek emergency medical attention if an overdose is suspected.

The most common symptom of a enoxacin overdose is seizures.

Missed Dose

Take the missed dose up to 2 hours late. If more than 2 hours have passed since the missed dose, skip it and take the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

Avoid excessive exposure to sunlight. Enoxacin increases the sensitivity of the skin to sunlight, and a severe sunburn may result. Wear protective clothing and sunscreen if sun exposure is unavoidable. Call your doctor if you experience severe burning, redness, swelling, blistering, itching, or a rash after exposure to sunlight.

Avoid excessive intake of caffeine-containing products such as coffee, tea, colas, and chocolate.

Use caution when driving, operating machinery, or performing other hazardous activities. Enoxacin may cause dizziness. If you experience dizziness, avoid these activities.

Brands

There are no brands containing this molecule.

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