In the condition known as empty sella syndrome, the pituitary gland flattens and shrinks. A small gland called the pituitary is found right below the brain. The pituitary stalk connects it to the base of the brain. In a saddle-like bone compartment at the skull base, the pituitary rests securely. This compartment is known as the sella.
On an MRI scan, the pituitary gland can’t be observed when it shrinks or flattens. As a result, the pituitary gland area seems to be “empty sella.” The sella is not, however, completely empty. Cerebrospinal fluid is frequently present inside. The fluid that envelops the brain and spinal cord is called CSF. CSF leaks into the sella turcica in empty sella syndrome, placing pressure on the pituitary. The gland flattens or shrinks as a result of this.