EFFIENT

Do not use Effient in people with the following conditions:

• Active pathological bleeding: Effient should not be used in individuals who currently have significant bleeding, such as gastrointestinal bleeding, intracranial bleeding, or active peptic ulcer disease. It can exacerbate bleeding and increase the risk of further complications.
• History of stroke or transient ischemic attack (TIA): Effient is contraindicated in individuals who have had a stroke or TIA in the past, as it may increase the risk of recurrent stroke.
• Hypersensitivity: Effient should not be used in individuals with known hypersensitivity or previous allergic reactions to the medication or any of its components.
• Severe liver disease: Effient is contraindicated in individuals with severe liver impairment, as it can affect the metabolism and elimination of the medication.
• Severe renal impairment: Effient is not recommended for individuals with severe kidney (renal) impairment, as it can affect the clearance of the medication from the body.
• Concomitant use of strong CYP3A inhibitors: Effient should not be used in combination with strong inhibitors of the enzyme CYP3A, as it can lead to increased levels of Effient in the body, increasing the risk of bleeding.

Effient may have the following side effects:

• Bleeding: Effient significantly increases the risk of bleeding. This can manifest as easy bruising, nosebleeds, bleeding gums, prolonged bleeding from cuts or wounds, blood in the urine or stools, or heavy menstrual bleeding. It is important to promptly inform your healthcare provider if you experience any unusual or excessive bleeding.
• Headache: Headaches are a common side effect of Effient. In most cases, they are mild and resolve on their own. However, if you experience severe or persistent headaches, it is recommended to consult with your healthcare professional.
• Upset stomach: Effient can cause gastrointestinal side effects such as nausea, vomiting, or stomach discomfort. These symptoms are generally mild and temporary.
• Diarrhea: Some individuals may experience diarrhea while taking Effient. In most cases, it is self-limiting and does not require treatment. However, if diarrhea becomes severe or persistent, it is advisable to seek medical advice.
• Shortness of breath: In rare cases, Effient can cause shortness of breath or difficulty breathing. If you experience these symptoms, it could be a sign of a serious allergic reaction and requires immediate medical attention.
• Allergic reactions: Although uncommon, some individuals may develop allergic reactions to Effient. Symptoms may include rash, itching, swelling, dizziness, or difficulty breathing. If you notice any signs of an allergic reaction, seek immediate medical attention.

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

• Bleeding risk: Effient increases the risk of bleeding, so it is important to be cautious, especially if you have a history of bleeding disorders or are taking other medications that increase the risk of bleeding, such as blood thinners or nonsteroidal anti-inflammatory drugs (NSAIDs). Inform your healthcare provider about any bleeding tendencies or medications you are taking.
• Inform healthcare providers: Make sure to inform all healthcare providers, including dentists and surgeons, that you are taking Effient before any procedures or surgeries. Effient may need to be temporarily stopped prior to certain procedures to minimize the risk of excessive bleeding.
• Allergic reactions: If you have had an allergic reaction to Effient or any other medications in the past, it is important to inform your healthcare provider. Allergic reactions can be serious and require immediate medical attention.
• Liver or kidney problems: Individuals with severe liver or kidney problems may need special monitoring or dose adjustments when taking Effient. Make sure to inform your healthcare provider if you have any underlying liver or kidney conditions.
• Pregnancy and breastfeeding: Effient is not recommended during pregnancy, as it may harm the fetus. If you are pregnant or planning to become pregnant, discuss the risks and benefits of Effient with your healthcare provider. It is also not known whether Effient passes into breast milk, so it is advisable to consult your healthcare provider before taking Effient while breastfeeding.

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Effient may interact with the following medicines:

• Blood thinners: Taking Effient with other blood-thinning medications, such as anticoagulants (e.g., warfarin, heparin) or antiplatelet drugs (e.g., aspirin), can increase the risk of bleeding. Your healthcare provider will closely monitor your condition and adjust the dosage as needed.
• Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs, including ibuprofen and naproxen, can also increase the risk of bleeding when combined with Effient. It is advisable to consult your healthcare provider before taking any NSAIDs while on Effient.
• Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs): Some antidepressant medications, such as fluoxetine, sertraline, and venlafaxine, can increase the risk of bleeding when taken with Effient. Your healthcare provider will assess the risks and benefits of combining these medications.
• Proton pump inhibitors (PPIs): PPIs, commonly used to reduce stomach acid, can reduce the effectiveness of Effient. Examples of PPIs include omeprazole, esomeprazole, and pantoprazole. Your healthcare provider may recommend alternative medications to manage stomach acid if you are taking Effient.
• Drugs affecting liver enzymes: Certain medications that affect liver enzymes, such as rifampin or carbamazepine, may alter the way Effient is metabolized in the body. This can potentially reduce the effectiveness of Effient. Inform your healthcare provider about all the medications you are taking, including those for other medical conditions.

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you suspect an overdose, contact your doctor right away.

Available Brands:

• Prasugrel