DIPYRIDAMOLE

Not available.

Common side effects:

• Dizziness,
• stomach upset,
• diarrhea,
• vomiting,
• headache, and
• flushing

Tell your doctor right away if you have any serious side effects, including:

• fainting,
• stomach pain,
• yellowing eyes/skin,
• dark urine,
• unusual bleeding/bruising.

Get medical help right away if you have any very serious side effects, including: chest pain, severe headache, weakness on one side of the body, vision changes, slurred speech, confusion.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Precautions:

• Allergy: Before taking dipyridamole, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
• Medical History: Before using this medication, tell your doctor or pharmacist if you had: other heart problems (such as severe coronary artery disease, recent heart attack), low blood pressure (hypotension), liver disease, a certain muscle problem (myasthenia gravis).
• Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
• Coronary Artery Disease: Dipyridamole has a vasodilatory effect and should be used with caution in patients with severe coronary artery disease (e.g., unstable angina or recently sustained myocardial infarction). Chest pain may be aggravated in patients with underlying coronary artery disease who are receiving dipyridamole.
• Hepatic insufficiency: Elevation of liver enzymes and hepatic failure have been reported in association with dipyridamole.
• Hypotension: Should be used with caution in patients with hypotension as it may lead to peripheral vasodilation.

Pregnancy Risk: Category B. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

Breastfeeding: This medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions:

• Some products that may interact with this drug include: riociguat, other antiplatelet drugs (such as abciximab, ticlopidine).
• If you are currently taking aspirin, talk to your doctor right away and ask if you should continue taking it with this medication. If you are not currently taking aspirin, talk to your doctor before starting it for any medical condition.

This medication is sometimes used together with other drugs that may increase your risk of bleeding. Examples are certain “blood thinners” (such as heparin, warfarin).

Overdose:

If overdose is suspected, contact a poison control center or emergency room immediately.

Symptoms of overdose may include: flushing, sweating, restlessness, weakness, dizziness, fast heartbeat.

Notes

Do not share this medication with others.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Brands:

Also marketed as

• Persantin [ Boehringer Ingelheim ]
• Persantin Ampoule [ Boehringer Ingelheim ]
• Prexin [ LR Imperial ]