COMMON BRAND NAME(S): Persantine
GENERIC NAME(S): DIPYRIDAMOLE
Description: Dipyridamole inhibits the platelet from sticking together and may cause vasodilation. It inhibits the uptake of adenosine into platelets, endothelial cells and erythrocytes.
Absorption: Absorbed incompletely from the GIT (oral); peak plasma concentrations after 75 min.
Distribution: Protein-binding: Highly bound.
Metabolism: Hepatic; there is enterohepatic recirculation.
Excretion: Via bile (as glucuronides); 10-12 hrs (elimination half-life).