Contraindications: | Epilepsy or other convulsive disorders, cerebral oedema, cerebrovascular accident, head injury, acute severe asthma, physical obstruction of the airway, severe hypertension, ischaemic heart disease, hyperthyroidism, pheochromocytoma. |
Special Precautions: | Less severe degrees of hypertension, impaired cardiac reserve; liver dysfunction. |
Adverse Drug Reactions: | Dyspnoea, resp problems; muscular, GI, CNS and CV effects. |
Drug Interactions: | Anaesthetics, sympathomimetics, MAOIs, neuromuscular blockers. |
Mechanism of Action: | Description: Dimefline is a central and resp stimulant with a brief duration of action. It acts by stimulation of peripheral chemoreceptors and central resp centers. |
Therapeutic Category: | Respiratory Stimulants |