Dientamoeba fragilis infection (D. fragilis) is caused by a parasite in the human large intestine. It is a parasite with only one cell. There is no conclusive evidence about whether an infection caused by Dientamoeba fragilis results in sickness. D. fragilis is frequently seen in the feces of healthy individuals and those with diarrhea or other intestinal symptoms.


Many persons who have dientamoeba fragilis infection don’t exhibit any symptoms. The most typical signs are:

  • Diarrhea
  • fatigue
  • loss of appetite
  • nausea
  • stomach cramping
  • stomach pain
  • weight loss


Your doctor will request stool samples from you to identify dientamoeba fragilis infection. You could be asked to give stool samples for more than one day since the parasite is not always present in every sample of feces. Pinworm eggs may also be checked for as they are frequently (though not always) discovered in people with Dientamoeba fragilis infection.


The patient’s age and clinical state will determine the treatment given. A short-term treatment will be provided to the patient, regardless of age, to determine whether it may lessen symptoms; if not, a new diagnosis and course of action are required. If the youngster exhibits no symptoms, treatment is not needed.

There are treatments for infections caused by Dientamoeba fragilis. The doctor may need to consider other potential reasons for a patient’s symptoms because they are not always successful in easing symptoms.

Typically, the doctor would suggest the following prescription medications:

  • Iodoquinol
  • Metronidazole
  • Paromomycin
  • Secnidazole and ornidazole
  • Tetracycline and doxycycline 

Dientamoeba Fragilis Infection Prevention

The following are methods for avoiding infection.

  • There is no reason to exclude those with a proven D. fragilis infection but no symptoms.
  • People experiencing diarrhea should stay home from daycare, preschool, school, and work until it has stopped for at least 24 hours. When working as a food handler in a restaurant, the exclusion period should last until 48 hours without any diarrhea or vomiting.
  • Infants, kids, and constipated adults shouldn’t go swimming until they have been constipated-free for 24 hours.
  • Observe proper cleaning and hand-washing techniques.

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