Darzalex is used in the following conditions:

  • Used in combination with certain chemotherapy medicines to treat multiple myeloma in adults
  • Used to treat adults with relapsed or refractory multiple myeloma who have received at least three prior lines of therapy

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Darzalex in people with the following conditions:

  • Hypersensitivity

There are no known contraindications for Daratumumab. However, it is important to note that Daratumumab should not be given to patients who have had a severe reaction to a previous dose of the drug. Additionally, Daratumumab should not be given to patients who have an active infection.

Darzalex may have the following side effects:

  • Common side effects of daratumumab include fatigue, infusion-related reactions, upper respiratory tract infection, low white blood cell count, low red blood cell count, low platelet count, anemia, nausea, back pain, constipation, cough, headache, rash, and diarrhea
  • Less common side effects include urinary tract infection, joint pain, flu-like symptoms, and low levels of certain proteins in the blood. Serious side effects include allergic reactions and infections

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.
This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.


Take extra caution in patients with the following medical conditions:

  • Active infection, severe renal impairment, and a history of allergic reactions to other monoclonal antibodies
  • Patients should also be monitored for signs and symptoms of infusion-related reactions, including fever, chills, hypotension, wheezing, and rash
  • Patients should also be monitored for signs and symptoms of anemia, neutropenia, thrombocytopenia, and other hematologic adverse reactions
  • Patients should also be monitored for signs and symptoms of secondary malignancies, including skin cancer, lymphomas, and leukemia, as daratumumab may increase the risk of these complications
  • It should also be used with caution in patients with severe hepatic impairment

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.


Darzalex may interact with the following medicines:

  • Chemotherapy drugs, such as bortezomib, lenalidomide, and pomalidomide, as well as certain anticoagulants, such as warfarin, heparin, and low-molecular-weight heparins
  • Other medications that affect the immune system, such as corticosteroids, cyclosporine, sirolimus, tacrolimus, and mycophenolate

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you suspect an overdose, contact your doctor right away.

Available Brands:

  • Darzalex

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