Dactive is an imidazopyridine compound that interacts with the GABA receptor complex’s benzodiazepine (BZD) channels, causing reduced neuronal excitability, enhanced chloride conductance, action potential suppression, and neuronal hyperpolarisation. Because its preference is the BZ1-receptor over the BZ2-receptor, it has a substantial sedative effect but relatively little anticonvulsant, myorelaxant, and anxiolytic.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully. 

Your physician’s medication dose is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage; take it regularly or as instructed by your physician. Adverse events may still happen even at usual prescription dosages. 

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. Take it at a fixed time every day to make you remember it better. 

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions. 

If you have any inquiries regarding information, ask your physician or pharmacist.

Dactive is used in the following conditions:

  • Insomnia treatment in the short term

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Dactive in people with the following conditions:

  • Severe liver problem

Dactive may have the following side effects:

  • Angioedema
  • Hepatitis
  • Abnormal LFT
  • Enhanced ALT serum concentrations
  • Visual problems
  • Fatigue
  • Lower and upper respiratory tract infection
  • GI disturbances
  • Amnesia
  • Rebound insomnia
  • Ataxia
  • Drowsiness
  • Vertigo
  • Dizziness
  • Vomiting
  • Nausea 
  • Headache
  • Somnambulism
  • Somnolence
  • Hallucination
  • Atypical thinking and behaviour

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.  

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling of the face or tongue or throat, dizziness or difficulty breathing. 

This is not a complete list of side effects. Contact your physician or pharmacist if you see other effects not recorded above.

Take extra caution in patients with the following medical conditions:

  • Lactation
  • Pregnancy
  • If insomnia does not resolve within 7-10 days, it might suggest the existence of underlying psychological and physical issues.
  • After extended treatment, prevent accidental cessation and quick dosage decrease.
  • Addiction to drugs or alcohol in the past
  • Patients displaying depressive symptoms
  • Impaired respiratory function  
  • Obstructive sleep apnea

Before taking this medicine, tell your physician or pharmacist if you are allergic to it or if you have some other hypersensitivities. This drug may contain inert ingredients, which can cause unfavourable side effects or different issues. Talk with your pharmacist for more information.


Dactive may interact with the following medicines:

  • CYP3A4 inhibitors
  • Ketoconazole
  • Itraconazole
  • Chlorpromazine
  • Imipramine
  • CNS depressants 
  • Flumazenil

Inform your physician about the drugs you take, including over-the-counter medications, prescribed drugs, supplements and vitamins. 

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details. 

The effects of certain medications can change if you simultaneously consume different medications or herbal products. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking. 

While utilizing this drug, don’t start, stop, or change the dose of other medicines you use without your physician’s advice.

Symptoms of overdose may include the following: 

  • Impaired respiratory and CV function
  • Consciousness disorders ranging from somnolence to coma
  • Sleeplessness

Seek medical help immediately. 

Available Brands:

  • Zolfit
  • Zolep
  • Zoldem
  • Zolcent 
  • Isodem
  • Dactive
  • Ambulax-Z 
  • Ambiz

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