CETIRIZINE-PSEUDOEPHEDRINE

Cetirizine and Pseudoephedrine is a drug combination that helps relieve allergy symptoms such as watery eyes, runny or stuffy nose and itchiness of the nose or eyes. Cetirizine is an antihistamine that reduces that effect of the chemical histamine in the body during allergic reaction.  Pseudoephedrine is a decongestant that helps decrease swelling and congestion by narrowing the blood vessels in the nose.

This medication is used to treat allergy symptoms like sneezing, watery eyes, runny nose or stuffy nose and itchy eyes or nose.

Do not use this medication:

  • If you are allergic to any ingredient in Cetirizine and Pseudoephedrine or if you have other allergies.
  • If you have certain medical conditions like narrow-angle glaucoma, severe difficulty urinating, very high blood pressure, or severe heart or blood vessel disease.
  • If you are currently taking or have taken Furazolidone or a Monoamine Oxidase (MAO) inhibitor (eg, Phenelzine) within the last 14 days.
  • To children under 12 years of age due to the large amount of Pseudoephedrine in it.

Common side effects may include:

  • Sleepiness or Unusual Drowsiness
  • Extreme Tiredness

Less common side effects are:

  • Dry Mouth
  • Weakness

Notify your doctor promptly if any of these symptoms persist or worsen.

Rare side effects may include:

  • Sore Throat
  • Breathing, Troubled
  • Back, Leg, or Stomach Pain
  • Blurred Vision
  • Bloody, Cloudy, or Dark Urine, Sudden Decrease in Amount of Urine
  • Black, Tarry Stools, Diarrhea, Light-Colored Stools
  • Confusion
  • Dizziness, Feeling Faint, or Lightheaded
  • Fever or Chills
  • Increased Blood Pressure

Some side effects may occur that usually do not need medical attention. Your doctor may have prescribed this medication because he or she judged that the benefit to you is greater than the risk of side effects.

Precautions

Before taking this drug, tell your doctor or pharmacist:

  • If you are allergic to the content of this drug or if you have any other allergies.
  • Pregnant or breastfeeding.
  • If you have certain medical conditions that requires you to be cautious with your other drug intake.

This drug may cause dizziness, drowsiness or blurred vision. Avoid activities requiring alertness or clear vision such as driving until you are sure you can perform such activities safely. Limit the use of alcohol and certain other medications that cause drowsiness.

The decongestant in this medicine may cause some people to be nervous or restless or to have trouble in sleeping. If you have trouble in sleeping, take the last dose of this medicine for each day a few hours before bedtime. Check with your doctor if you have any questions about this.

 

Interactions

Drug interactions may either lessen the effectiveness of this drug or heighten the risk for severe side effects. It’s important to inform your doctor all the medication including prescription and non-prescription and herbal medicines you are taking or going to take.

Possible interactions with this drug are:

  • MAO inhibitors like Isocarboxazid, Linezolid, Methylene Blue, and Moclobemide.
  • Opioid pain or cough relievers (such as codeine, hydrocodone) for they can increase drowsiness.
  • Alcohol
  • Drugs for Sleep or Anxiety (such as Alprazolam, Lorazepam, Zolpidem)
  • Muscle Relaxants (such as Carisoprodol, Cyclobenzaprine)
  • Antihistamine applied to the skin (such as diphenhydramine cream, ointment, spray) because increased side effects may occur.
  • Other Antihistamines (such as Chlorpheniramine, Diphenhydramine)
  • Levocetirizine because it is similar to Cetirizine.

Inform your doctor and laboratory personnel that you are using this drug if you are going to undergone certain laboratory tests. This drug may interfere with the result and may give false results.

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Symptoms of overdose may include:

  • Severe Drowsiness
  • Fast or Irregular Heartbeat
  • Mental or Mood Changes (such as Anxiety, Restlessness)
  • Seizures

 

Available brand/s:

Zyrtec-D

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