Description: Cefixime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Cefixime, a cephalosporin antibiotic, treats a wide variety of bacterial infections by stopping the growth of bacteria. This antibiotic treats only bacterial infections.

How to use cefixime

Take this medication by mouth with or without food as directed by your doctor, usually once a day. In children, this medication may also be taken twice a day (every 12 hours). If you are taking the chewable tablets, chew thoroughly and then swallow.

The dosage is based on your medical condition and response to treatment. In children, the dosage is also based on weight.

Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.

Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.

Tell your doctor if your condition persists or worsens.

Notify your doctor or pharmacist promptly if any of these effects persist or worsen:

  • Stomach upset/pain
  • Diarrhea
  • Nausea
  • Gas
  • Headache
  • Dizziness

Tell your doctor immediately if any of these rare but very serious side effects occur:

  • severe stomach/abdominal pain
  • persistent nausea/vomiting
  • yellowing eyes/skin
  • dark urine
  • unusual tiredness
  • new signs of infection (e.g., persistent sore throat, fever)
  • easy bruising/bleeding
  • change in the amount of urine
  • mental/mood changes (such as confusion)

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant bacteria. This condition may occur weeks to months after treatment has stopped.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection).

A very serious allergic reaction to this drug is rare.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.


  • Allergic reaction to this medication.
  • Patients with medical history of kidney disease or a certain intestinal disease (colitis).
  • Tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before having surgery.
  • Condition that requires you to limit/avoid aspartame (or phenylalanine) in your diet.
  • Used only when clearly needed during pregnancy.
  • Consult your doctor before breast-feeding.

Consult your doctor regarding the precautions mentioned above.



Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions.

“Blood thinners” (e.g., warfarin) and live bacterial vaccines may interact with this drug.

Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness.

This medication may cause false positive results with certain diabetic urine testing products (cupric sulfate-type). This drug may also affect the results of certain lab tests.


If overdose is suspected, contact a poison control center or emergency room immediately. Symptoms of overdose may include severe vomiting, seizures.

Notes: Do not share this medication with others.

This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases.

Missed Dose: For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule. Do not double the dose to catch up.

Storage: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.



Available Brands

  • Actimax [ PSA ]
  • Cefsea 25 [ Medchem Int’l ]
  • Ceftrimed [ Biolink Pharma ]
  • Cefzin [ Biopharma ]
  • Dinofix [ DNBG Pharma ]
  • Evofix [ PharmEvo ]
  • Ezcef-100/Ezcef-200/Ezcef [ EON Pharmatek ]
  • Fexitas [ Parabolic Drugs ]
  • Fix-A [ ACME ]
  • Fixcef [ Bosch ]
  • Fixim [ Lark Lab ]
  • Fixxx [ XL Lab ]
  • Gracefix [ Ambica ]
  • Mycefix [ Scott-Edil ]
  • Pharex Cefixime [ XL Lab ]
  • Retracef [ ACME ]
  • RiteMED Cefixime [ RiteMED ]
  • Septipan [ Geofman ]
  • Taxim-O/Taxim-O Forte [ Alkem Lab ]
  • Tergecef [ UAP ]
  • Trifix [ Vamsler ]
  • Trifixime [ InnoGen Pharmaceuticals ]
  • Triocef [ Cathay Drug ]
  • Trufix [ Pasteur Pharma ]
  • Ultraxime [ Pediatrica ]
  • Zefitas [ Umedica ]

Also marketed as

  • Aeruxim [ Shenzhen Zhijun ]
  • Axetef [ Domesco ]
  • Cefimax [ Eurowest ]
  • Cefixmycin [ Yung Shin ]
  • Cexime [ Korea United Pharma ]
  • Cifacure-100/Cifacure-200/Cifacure [ Medchem Int’l ]
  • Citroen [ ACME ]
  • C-Tax P [ Emcure Pharma ]
  • Dancef-DS [ PharmEvo ]
  • Fixma 200 [ Clesstra Healthcare ]
  • Fixxx-DS [ PharmEvo ]
  • Refixime [ XL Lab ]
  • Surixime-200/Surixime [ Galpha Lab ]
  • Synmex [ One Pharma ]
  • Taxocef-O [ Sel-J Pharma ]
  • Zefaxim [ Platinum Pharma ]
  • Zefral [ UAP ]

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