CARBINOXAMINE

GENERIC NAME(S): PSEUDOEPHEDRINE HCL/CARBINOXAMINE MALEATE

 

Description: Carbinoxamine is a monoethanolamine derivative (1st generation antihistamine with antimuscarinic and serotonin antagonistic effects) that can cause profound sedation.

This combination medication is used to temporarily relieve symptoms caused by the common cold, flu,allergies, or other breathing illnesses (such as sinusitis,bronchitis). Antihistamines, pseudoepehedrine HCl, help relieve watery eyes, itchy eyes/nose/throat, runny nose, and sneezing. Decongestants, carbinoxamine maleate, help to relieve stuffy nose and ear congestion symptoms.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. These products do not cure or shorten the length of the common cold and may cause serious side effects. To

How to use carbinoxamine

Take this medication by mouth as directed by your doctor. If you are self-treating, follow all directions on the

product package. If you are uncertain about any of the information, ask your doctor or pharmacist.

This medication may be taken with food if stomach upset occurs. Drink plenty of fluids unless otherwise directed by your doctor.

If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.

Do not crush or chew extended-release tablets or capsules. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

If you are using chewable tablets, chew each tablet thoroughly before swallowing.

If you are using a product made to dissolve in the mouth(tablets/strips), dry your hands before handling the medication. Place each dose on the tongue and allow to dissolve completely, then swallow it with saliva or with water.

Dosage is based on the product you are taking and your age, medical condition, and response to treatment. Do not increase your dose or take this medication more often than directed without your doctor’s approval. Improper use (abuse) of this medication may result in serious harm (such as hallucinations, seizure, death).

If your doctor directs you to take this medication daily, take it regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Tell your doctor if your condition persists for more than 1 week, if it worsens, or if it occurs with fever, rash, or persistent headache. These may be symptoms of a serious medical problem and should be checked by a doctor.

Tell your doctor or pharmacist promptly if any of these effects persist or worsen:

  • drowsiness
  • dizziness
  • dry mouth/nose/throat
  • headache
  • upset stomach
  • constipation
  • trouble sleeping

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • mental/mood changes (such as confusion, hallucinations)
  • ringing in the ears
  • difficulty urinating
  • vision changes (such as blurred/double vision)

Seek immediate medical attention if fast/irregular heartbeat or seizure occur.

A very serious allergic reaction to this drug is rare.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

  • Allergic reaction to this medication.
  • Patients with medical history, especially of:
    • breathing problems (such as asthma,emphysema)
    • diabetes
    • glaucoma
    • heart problems
    • high blood pressure
    • kidney problems
    • liver disease
    • seizures
    • stomach/intestinal problems (such as ulcers, blockage)
    • overactive thyroid(hyperthyroidism)
    • difficulty urinating (such as due to enlarged prostate)
  • Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.
  • Condition that requires you to limit/avoid sugar, aspartame and alcohol in your diet.
  • Tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before having surgery.
  • Children may be more sensitive to excitation and agitation.
  • Older adults may be more sensitive to dizziness, drowsiness, confusion, constipation, fast/irregular heartbeat, trouble sleeping, or urination problems.
  • Used only when clearly needed during pregnancy.
  • Consult your doctor before breast-feeding.

Consult your doctor regarding the precautions mentioned above.

 

Interactions

The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur.

Some products that may interact with this drug are antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray) or blood pressure medications (especially reserpine, guanethidine, methyldopa, beta blockers such as atenolol, or calcium channel blockers such as nifedipine).

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with this medication.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine).

This medication may interfere with certain medical/laboratory tests (including brain scan for Parkinson’s disease), possibly causing false test results

This document does not contain all possible drug interactions.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. Symptoms of overdose may include severe dizziness, fainting, mental/mood changes (such as hallucinations).

Notes: If your doctor has prescribed this medication, do not share it with others.

Keep all regular medical and laboratory appointments.

Do not take this product for several days before allergy testing because test results can be affected.

Missed Dose: If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage: Store at room temperature away from light and moisture. Do not store in the bathroom. Do not freeze liquid forms of this medication. Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

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