BULLOUS PEMPHIGOID

BULLOUS PEMPHIGOID

Overview and Facts

Bullous pemphigoid is an uncommon skin condition that causes huge, liquid-filled pustules. They grow on some skin areas that regularly flex, for example, the lower abdomen, upper thighs, or armpits. For grown-ups, individual bullous pemphigoid is generally normal.

Bullous pemphigoid occurs when your immune system assaults a thin layer of tissue underneath your external layer of skin. The cause behind this unusual immune reaction is unexplainable, although it can be set off by taking certain drugs.

Bullous pemphigoid frequently disappears in a couple of months, yet may reach until five years to determine. Treatment for bullous pemphigoid may contain corticosteroid meds, such as prednisone and other medications that repress the immune system. Bullous pemphigoid can be dangerous, particularly for adults who have weak immune systems.

Types and Symptoms

SYMPTOMS

Bullous pemphigoid has the following signs and symptoms:

  • Tingling skin, weeks or months before blisters develop.
  • Huge blisters that don’t break when contacted, frequently along creases or overlap in the skin 
  • The skin around the blisters is typical, rosy, or darker than ordinary 
  • Skin infection or a hive such as mini rash blisters
  • Mouth bruising or diagnosis of other mucous membranes

Diagnosis & Medications

DIAGNOSIS

To verify the diagnosis, a primary care physician may arrange blood tests and take a specimen of the affected area (skin biopsy) for laboratory testing. 

A primary care physician may refer a person with bullous pemphigoid to a dermatologist, a specialist in conditions involving the hair, skin, and nails, or eyes (ophthalmologist), depending upon the signs, indications and the outcome of the laboratory tests.

TREATMENT

Treatment is centered around healing the skin and diminishing tingling while at the same time limiting bad reactions to drugs. Your primary care physician will probably recommend one or a mix of the medications: 

Corticosteroids. The most widely recognized treatment is prednisone, which comes in pill form. In any case, long-term use can expand your danger of frail bones, diabetes, hypertension, elevated cholesterol, and disease. Corticosteroid ointment can be applied to your affected skin and causes a less adverse reaction. 

Steroid-saving medications. These medications affect the immune system by hindering the growth of the body’s infection battling white platelets. Examples include azathioprine (Azasan, Imuran) and mycophenolate mofetil (CellCept). If the signs and symptoms include the eyes or upper gastrointestinal tract, the medication rituximab (Rituxan) might be consumed if other alternatives haven’t worked. 

Other medications that fight inflammation. The best example is methotrexate (Trexall).

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