BROLUCIZUMAB

Brolucizumab, a recombinant humanised monoclonal antibody inhibitor of vascular endothelial growth factor (VEGF), binds to three primary isoforms of VEGF-A with great affinity. Endothelial cell proliferation is repressed, neovascularization is diminished, and vascular permeability is lowered as a result.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

Uses

Brolucizumab is used in the following conditions:

Neovascular (wet) age-related macular degeneration

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Brolucizumab in people with the following conditions:

Active or suspected ocular or periocular infections
Active intraocular inflammation

Side Effects

Brolucizumab may have the following side effects:

Endophthalmitis
Retinal detachment
Intraocular inflammation
Traumatic cataract
Acute and sustained increases in intraocular pressure
Retinal vasculitis or retinal vascular occlusion
Antibody development
Non-ocular hemorrhages
Stroke
Myocardial infarction
Reduced visual acuity
Vitreous floaters
Conjunctival hemorrhage
Uveitis
Iritis
Vitreous detachment
Retinal tear
Eye pain
Blurred vision
Conjunctivitis
Retinal pigment epithelial tear
Corneal abrasion
Punctate keratitis
Hypersensitivity
Rash
Pruritus
Urticaria
Erythema

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more significant than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A severe allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

Poorly controlled glaucoma
Risk factors for retinal pigment epithelial tear
Large and/or high pigment epithelial retinal detachment
Retinal detachment or macular hole
History of stroke
Transient ischemic attack or myocardial infarction within the last 3 months

Prior in taking this medicine, tell your physician or pharmacist if you have allergies or other hypersensitivity reactions with the drug. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

There are no known interactions for Brolucizumab.

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are possible, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

Symptoms:

Increased intraocular pressure

If an overdose is suspected, call your health care provider immediately.

Available brands:

Beovu