COMMON BRAND NAME(S): Tracleer
GENERIC NAME(S): BOSENTAN
Description: Bosentan blocks endothelin receptors on smooth muscle promoting vasodilation. It improves exercise capacity and clinical worsening in patients with pulmonary arterial HTN.
COMMON BRAND NAME(S): Tracleer
GENERIC NAME(S): BOSENTAN
Description: Bosentan blocks endothelin receptors on smooth muscle promoting vasodilation. It improves exercise capacity and clinical worsening in patients with pulmonary arterial HTN.
Indications
Bosentan is used to treat high blood pressure in the lungs (pulmonary arterial hypertension).
Contraindications
Should not be given to:
How to use bosentan
Dosage:
Liver damage: Bosentan may rarely cause serious (possibly fatal) liver damage. Rarely, liver problems have happened in people after stopping treatment with bosentan. Your doctor will perform liver function tests before you start treatment and once a month during treatment. Tell your doctor right away if you notice dark urine, loss of appetite, persistent nausea/vomiting, stomach/abdominal pain, or yellowing eyes/skin.
Pregnancy: Bosentan must not be used during pregnancy because it may cause serious harm (such as birth defects) in an unborn baby. Women of childbearing age must have a negative pregnancy test before starting this medication and monthly during treatment. Use at least two reliable forms of birth control while taking bosentan and for at least one month after stopping bosentan as directed by your doctor to prevent pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away.
Common Side effects:
Tell your doctor immediately if any of these unlikely but serious side effects occur:
Tell your doctor immediately if any of these rare but very serious side effects occur: fainting, shortness of breath, coughing up blood.
In men, this medication can decrease sperm production, which may affect the ability to father a child. Talk to your doctor for more details.
Precautions
Pregnancy Risk: Category X. This medication must not be used during pregnancy. It may harm an unborn baby. Therefore, it is important to prevent pregnancy while using this medication.
Breastfeeding: It is not known whether this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.
Interactions
Overdose
If overdose is suspected, contact a poison control center or emergency room immediately.
Symptoms of overdose may include: severe headache, severe dizziness, nausea, vomiting.
Notes: Do not share this medication with others.
Laboratory and/or medical tests (such as liver function tests, pregnancy tests, hemoglobin, hematocrit) should be performed before you start treatment, and periodically to monitor your progress or check for side effects. Consult your doctor for more details.
Missed Dose: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Storage: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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