BARNIDIPINE

 

Description: Barnidipine belongs to a class of medicine called calcium channel blockers (CCBs), also called calcium antagonists. CCBs prevent calcium from entering cells of the heart and blood vessel walls, resulting in lower blood pressure. They relax and widen blood vessels by affecting the muscle cells in the arterial walls.

Treatment of hypertension

Barnidipine should not be given to patients with cardiogenic shock, recent heart attack or acute unstable angina, and severe aortic stenosis.

Cardiogenic shock is a condition in which the heart suddenly cannot pump enough blood to meet the body’s needs; it is most often caused by a severe heart attack. Unstable angina is a condition in which the heart does not get enough blood flow and oxygen; it may lead to a heart attack. Aortic stenosis is the narrowing of the aortic valve of the heart.

Dizziness; flushing; headache; hypotension (low blood pressure); peripheral edema; tachycardia (fast heartbeat); palpitations; gastrointestinal disturbances; increased urination frequency; lethargy; eye pain; depression; ischemic chest pain; brain or heart ischemia (inadequate blood supply); transient blindness; rashes; fever; abnormal liver function; gingival hyperplasia; myalgia (muscle pain); tremor; impotence.

Precautions

Give with caution in pregant/lactating women and patients with hypotension, poor cardiac reserve and heart failure. Sudden withdrawal may worsen chest pain. Discontinue in patients who experience ischemic pain following administration.

 

Interactions

Other antihypertensives; aldesleukin; antipsychotics that cause hypotension; may modify insulin and glucose responses; quinidine; carbamazepine; phenytoin; rifampicin; cimetidine; erythromycin.

If overdose is suspected, bring the victim to the hospital immediately.

Available brands:

  • HypoCa

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