Avanafil is a phosphodiesterase (PDE) inhibitor that brings about type 5-mediated metabolism of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum, which is responsible for the smooth muscle relaxation due to increased cGMP levels and sexual stimulation by increasing inflow of blood into the corpus cavernosum of the penis, thereby producing an erection. In the absence of sexual stimulation, this drug will not initiate its effect.


Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Avanafil is used in the following conditions:


  • Erectile dysfunction


This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Avanafil in people with the following conditions:


  • Unstable angina
  • Angina with sexual intercourse
  • Congestive heart failure
  • Hypotension
  • Stroke
  • Life-threatening arrhythmia
  • Conditions wherein sexual activity is inadvisable
  • Vision loss due to non-arteritic anterior ischemic optic neuropathy (NAION)
  • Hereditary degenerative retinal disorders
  • Severe renal and hepatic impairment
  • Concomitant use withany form of organic nitrate, guanylate cyclase stimulators, potent CYP3A4 enzyme inhibitors

Avanafil may have the following side effects:


  • Cardiovascular risk
  • Priapism
  • Sudden vision and hearing loss
  • Non-arteritic anterior ischemic optic neuropathy
  • Prolonged erection
  • Hypersensitivity reactions
  • Headache
  • Dizziness
  • Flushing
  • Electrocardiogram abnormality
  • Transient sitting hypotension
  • Viral gastroenteritis
  • Nasal congestion
  • Nasopharyngitis
  • Upper respiratory tract infection
  • Back pain
  • Impaired color discrimination
  • Tinnitus


Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more significant than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A severe allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:


  • Patient with risk factors or pre-existing cardiovascular disease
  • Left-ventricular outflow obstruction
  • Active peptic ulcer
  • Bleeding disorders
  • Risk factors for priapism
  • Penile deformation
  • Mild to moderate hepatic impairment
  • Patients receiving alpha-adrenergic blockers or moderate CYP3A4 enzyme inhibitors

Prior in taking this medicine, tell your physician or pharmacist if you have allergies  or other hypersensitivity reactions with the drug. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.




Avanafil may interact with the following medicines:


  • CYP3A4 enzyme inhibitors
  • Alpha-adrenergic blocking agents
  • Organic nitrate and guanylate cyclase stimulators

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are possible, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you think you have used Avanafil more than the usual dosage, please seek medical help immediately.


Symptoms of overdose may include the following:


  • Severe headache
  • Flushing
  • Nasopharyngitis
  • Nasal congestion
  • Back pain
  • Dizziness
  • Supportive treatment


Available Brands:


  • Stendra

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