There are 2 types of AIS.
- Complete androgen insensitivity syndrome (CAIS)
- Partial androgen insensitivity syndrome (PAIS)
A person with a CAIS develops full resistance to male hormones such as testosterone. The genitals of an individual with CAIS are that of a female. However, they have no uterus, and they don’t menstruate or become fertile.
Testosterone has minimal effects on the sexual development of an individual who suffers from PAIS. The genitals of a person with PAIS appears to be somewhere between a male and a female.
Symptoms of AIS varies between its types.
An individual with CAIS will experience the following symptoms when they reach puberty.
- Have no or little armpit or pubic hair
- Develops female characteristics, like breasts
- Failure to menstruate and become fertile
PAIS, on the other hand, can be detected during childhood. A person with PAIS has characteristics between males and females. Symptoms for persons with PAIS may vary depending on how they are raised.
- Children raised as boys will be infertile.
- PAIS children raised as girls will have no womb and won’t be able to get pregnant.
Other common types of leg ulcer include:
- Arterial leg ulcers
- Diabetic leg ulcers
- Malignant leg ulcers
- Traumatic leg ulcers
- Vasculitic leg ulcers
Ulcers in the foot are usually caused by diabetes.
Itching, pain, and swelling in the affected leg are characteristic symptoms of a venous leg ulcer.
Discoloration, hardening of the skin around the ulcer, and presence of a foul-smelling discharge may also be present when you have a venous leg ulcer.
If you have a venous leg ulcer, you may exhibit the following conditions:
- discoloration and darkening of the skin around the ulcer
- swollen ankles
- red, flaky, scaly and itchy skin on your legs
- swollen and enlarged veins on your legs
- hardened skin around the ulcer, which may make your leg feel hard
- a heavy feeling in your legs
- an unpleasant and foul-smelling discharge from the ulcer
- aching or swelling in your legs
Signs of an infection
Opportunistic pathogens could cause secondary bacterial infections due to the ulcer.
Symptoms of an infected leg ulcer may include:
- a green or unpleasant discharge coming from the ulcer
- redness and swelling of the skin around the ulcer
- worsening pain
- an unpleasant smell coming from the ulcer