This drug belongs to a class of drugs called DPP-4 inhibitors. A class of drugs refers to medications that work similarly. They are often used to treat similar conditions.

Normally, hormones are released into your bloodstream as you start to eat. They cause insulin to be released into your bloodstream, which helps pick up and store the carbohydrates and sugar from the meal. Alogliptin helps these hormones to continue the release of insulin to help lower your blood sugar levels.

This drug is used along with diet and exercise to manage high sugar levels caused by type 2 diabetes.

Don’t use it if you have type 1 diabetes or increased ketones in your urine or blood.

The most common side effects that occur with this drug are:

  • Stuffy or runny nose and sore throat
  • Headache
  • Cold-like symptoms


Do NOT use alogliptin/ pioglitazone if:

  • you are allergic to any ingredient in alogliptin/pioglitazone
  • you have bladder cancer or moderate to severe heart failure
  • you have type 1 diabetes
  • you have high blood or urine ketone levels (diabetic ketoacidosis)
  • you have a history of liver problems, including jaundice (yellowing of the skin or eyes), during therapy with a similar medicine called troglitazone

Notify your doctor or health care provider of your complete medical history to avoid complications.



Your doctor should manage all of your medications carefully because this drug can interact with other medications, herbs, or vitamins you might be taking. To know more about these interactions, talk to your doctor or pharmacist.

Contact emergency hotline or go to the emergency room immediately if you take too much or think you may have taken too much of this drug. Your blood sugar level may get too low.


Available brands:

  • Nesina
  • Kazano

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