Description: Allylestrenol is similar in structure and function to the female hormone, progesterone. It prepares the uterus to receive the fertilized ovum and suppresses uterine motility.

Allyestrenol is used to prevent threatened miscarriage, recurrent pregnancy loss and premature labor. It has also been studied as a treatment for benign prostatic hyperplasia in men, with encouraging results.

Discontinue the medication if there is sudden, partial or complete loss of vision, migraine and blood clot disorders.

Caution should be exercised in patients with history of epilepsy, migraine, asthma, heart or kidney disease, depression, diabetes and breastfeeding.

Allyestrenol may cause dizziness or drowsiness. Do not drive a car or operate machinery while taking this medication.

  • Gastrointestinal disturbances
  • Appetite/weight change
  • Fluid retention and edema
  • Acne, skin rash, urticaria
  • Depression
  • Headache, fever, fatigue
  • Breast changes
  • Hirsutism (unwanted, male-pattern hair growth in women)
  • Changes in libido (sexual drive)
  • Altered menstrual cycles or irregular menstrual bleeding (rare)


Discontinue medications if there is sudden partial or complete loss of vision, proptosis (abnormal protrusion or displacement of an eye) or diplopia (double vision); migraine and embolic disorders; epilepsy, migraine, asthma, cardiac or renal dysfunction.

Give with caution in lactating women and patients with history of depression, glucose tolerance and diabetic patients. May impair ability to drive and operate machinery. Sudden withdrawal of allyloestrenol should be avoided as it leads to intermittent breakthrough bleeding.



Enhanced clearance with enzyme-inducing drugs eg, carbamazepine, griseofulvin, phenobarbital, phenytoin and rifampicin. Ketoconazole may increase bioavailability of progesterone.

Potentially Fatal: Increased ciclosporin concentration.

If overdose is suspected, bring the victim to the hospital immediately.

Available brands:

  • Turinal

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