Agenesis of corpus callosum (ACC) is a congenital defect in which the connections between the child’s right and left portion of the brain are not fully developed. It affects 1 to 7 out of every 4,000 babies born, according to statistics.

The corpus callosum binds the left and right sides of the brain. It is made up of 200 million nerve fibers that transmit information.

Additionally, agenesis of the corpus callosum (ACC) can manifest itself in a variety of ways, including:

  • Dysgenesis of the corpus callosum
  • Partial corpus callosum agenesis
  • Hypogenesis of the corpus callosum
  • Hypoplasia of the corpus callosum


The most common symptoms of agenesis of corpus callosum (ACC) include:

  • Vision issues
  • Seizures
  • Hearing loss
  • Poor muscle tone
  • Chronic stomach problems
  • Trouble sleeping
  • High pain tolerance
  • Problems seeing other people’s opinion
  • Social immaturity
  • Diminished coordination
  • Poor understanding of idioms, slang, or social cues
  • Problems interpreting facial expressions
  • Difficulty with reasoning
  • Difficulty distinguishing truth from untruth
  • Attention-deficit
  • Fearfulness
  • Obsessive behaviors 

Moreover, a child born with ACC can survive the disease. However, it may start causing developmental delays, which can range from moderate to severe.

For instance, ACC might impede a child’s growth of motor functions, like walking, sitting, and riding bikes. It also has the potential to make eating and swallowing more difficult. Children with this syndrome frequently have poor coordination.


If your child develops agenesis of corpus callosum (ACC), their doctor will be able to discover it through an ultrasound scan before they are born.  They might order an MRI if they discover symptoms. This will help them verify the diagnosis.

Furthermore, your child’s condition may also go unnoticed until after birth in some situations. If their doctor suspects they have acquired the disease, an MRI or CT scan might be ordered to rule out the problems.


Although there is no treatment for agenesis of corpus callosum (ACC), your child’s doctor may be able to provide medications to help control their symptoms. 

For instance, they may prescribe drugs to help manage seizures. Other therapies, such as physical, speech, or occupational therapy, may be recommended to support your child cope with other symptoms.

Your child with ACC might be able to live a healthy and long life, depending on the severity of their disease. Talk with the doctor about their condition and treatment choices.

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