|Indications:||Management of chronic asthma, allergic rhinitis & prophylaxis for exercise-induced asthma.|
|Dosage:||Childn 6-14 yr 5 mg; 2-5 yr 4 mg. All doses to be taken once daily in the evening.|
|Administration:||May be taken with or without food.|
|Special Precautions:||Systemic eosinophilia may occur. Avoid abrupt substitution to inhaled or oral corticosteroids. Concomitant use w/ NSAIDs in patients w/ known aspirin sensitivity. Not for treatment of acute asthma attacks. Pregnancy & lactation.|
|Side Effects / Adverse Reactions:||Headache, dizziness; abdominal pain, dyspepsia, infectious gastroenteritis; influenza, cough, nasal congestion; fatigue, dental pain, rash, fever, trauma.
|Drug Interactions:||Potent hepatic enzyme inducers eg phenytoin, phenobarb or rifampicin.|
|Pregnancy Category (US FDA):||
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1sttrimester (and there is no evidence of a risk in later trimesters).
|Therapeutic Category:||Antiasthmatic & COPD Preparations|
|ATC Classification:||R03DC03 – montelukast ; Belongs to the class of leukotriene receptor antagonists. Used in the systemic treatment of obstructive airway diseases.|