Acetaminophen is used to relieve pain and reduce fever. Dextromethorphan (DM) is a cough suppressant that reduces the urge to cough by affecting certain part of the brain. Diphenhydramine is an antihistamine and works by reducing the symptoms brought by the natural substance histamine to our body such as watery eyes, runny nose and sneezing.

This combination medication is used to treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis), temporarily. This medication may also be used in other conditions to be determined by your doctor.

Do not use this drug:

  • More than prescribed. Too much intake of Acetaminophen may cause damage to your liver.
  • If you are allergic to Acetaminophen, Dextromethorphan or Diphenhydramine.

Common side effects may include:

  • Headache
  • Sleep Problems (Insomnia)
  • Upset Stomach
  • Diarrhea or Constipation
  • Dry Eyes
  • Blurred Vision
  • Dry Mouth Or Nose
  • Mild Dizziness or Drowsiness
  • Trouble Concentrating
  • Feeling Restless or Excited (Especially in Children)
  • Mild Skin Rash

Notify your doctor promptly if any of these symptoms persist or worsen.

Your doctor may have prescribed this medication because he or she judged that the benefit to you is greater than the risk of side effects.

Serious side effects may include:

  • Severe Allergic Reaction
  • Severe Headache
  • Seizure (Convulsions)
  • Fast, Pounding, or Uneven Heartbeats
  • Confusion
  • Hallucinations
  • Severe Dizziness or Drowsiness
  • Slow or Shallow Breathing
  • Tremor
  • Restless Muscle Movements
  • Little or No Urinating
  • Flu Symptoms
  • Easy Bruising
  • Unusual Bleeding
  • Pale Skin
  • Weakness
  • Feeling Light-Headed
  • Nausea
  • Pain In Your Upper Stomach
  • Itching
  • Loss of Appetite
  • Dark Urine
  • Clay-Colored Stools
  • Jaundice (Yellowing of the Skin or Eyes)

Seek immediate medical attention if you experience any of these serious side effects.


Before taking this drug, tell your doctor or pharmacist:

  • If you are allergic to any of its content or if you have other allergies.
  • If you are pregnant or breastfeeding.
  • If you have a history of alcohol abuse or if you are drinking 3 alcoholic beverages per day.
  • Your medical condition, especially of:
  • Severe Constipation, Blockage In Your Stomach or Intestines
  • Glaucoma
  • Asthma
  • High Blood Pressure
  • Heart Disease or Coronary Artery Disease
  • Overactive Thyroid
  • Kidney Disease
  • Cough With Mucus or Cough Caused by Emphysema or Chronic Bronchitis
  • An Enlarged Prostate
  • Problems with Urination



Drug interactions may either lessen the effectiveness of this drug or heighten the risk for severe side effects. It’s important to inform your doctor all the medication including prescription and non-prescription and herbal medicines you are taking or going to take.

Possible interactions with this drug are:

  • Alcohol
  • MAO Inhibitor (Furazolidone, Isocarboxazid, Linezolid, Phenelzine, Rasagiline, Selegiline, And Tranylcypromine)
  • Potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K)

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Symptoms of overdose may include:

  • Loss of Appetite
  • Nausea
  • Vomiting
  • Stomach Pain
  • Sweating
  • Confusion
  • Weakness
  • Upper Stomach
  • Dark Urine
  • Yellowing of your Skin or the Whites of your Eyes

Available brand/s:

  • Benadryl AH
  • Benaxil

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