Pentazocine is an opioid analgesic with agonist/antagonist action. Paracetamol is a peripherally and centrally acting antipyretic and analgesic. The combination gives additive analgesic effects.
Pentazocine is an opioid analgesic with agonist/antagonist action. Paracetamol is a peripherally and centrally acting antipyretic and analgesic. The combination gives additive analgesic effects.
Paracetamol + Pentazocine is used in the relief of mild to moderate pain.
Paracetamol + Pentazocine should not be given to patients with hypersensitivity to either component. It should also be avoided in raised intercranial pressure or head injury.
Paracetamol + Pentazocine can bring about side effects such as the following:
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Precautions
Take precautions in patients with the following medical conditions:
Interactions
Paracetamol + Pentazocine may interact with the following medicines:
Symptoms of overdose would be a combination of those observed with pentazocine overdose and paracetamol overdose. Overdose of Pentazocine may lead to anxiety, strange thoughts, hallucinations and nightmares.
Increased BP and tachycardia associated with marked respiratory depression may also occur. Acute paracetamol overdose may cause nausea, vomiting, anorexia and abdominal pain. Severe overdosage may lead to potentially fatal hepatic necrosis. Oxygen, IV fluids, vasopressors and other supportive measures involves in the treatment.
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