FLOCTAFENINE

Floctafenine is an NSAID, which is an anthranilic acid derivative related to glafenine.

Uses

Floctafenine is used in pain relief.

Warnings

Floctafenine should not be used in people with the following conditions:

  • Porphyria
  • Hypersensitivity
  • Peptic ulceration
  • Moderate/severe renal impairment
  • Diabetes
  • Hypertension
  • Pregnant or breastfeeding woman
  • Hepatitis
  • Cardiac diseases

Side Effects

Floctafenine can give rise to the following side effects:

  • GI disturbances
  • CNS effects
  • Hypersensitivity reactions
  • Blood disorders
  • Nephrotoxicity
  • Haematuria
  • Edema
  • Pancreatitis
  • Toxic epidermal necrolysis
  • Alveolitis
  • Stevens-Johnson syndrome
  • Photosensitivity
  • Pulmonary eosinophilia

Precautions

Precautions

Take precautions in patients with the following conditions:

  • Infection
  • Haemorrhagic disorders
  • Hypertension
  • Cardiac function
  • Asthma
  • Diabetes mellitus
  • Haemorrhoids
  • Rectal irritation or bleeding
  • Systemic lupus erythematosus
  • Epilepsy
  • Edema
  • Mental illness
  • Parkinson’s disease
  • Polymyalgia rheumatic
  • Temporal arthritis
  • Pregnancy and lactation

 

Interactions

Floctafenine can interact with the following medicines:

  • Oral anticoagulants
  • Antivirals
  • Phenytoin
  • Sulfonylurea antidiabetic
  • Methotrexate
  • Cardiac glycosides
  • ACE inhibitors
  • Diuretics
  • β-blocker
  • Other NSAIDs
  • Lithium
  • Ciclosporin
  • Tacrolimus
  • Moclobemide
  • Quinolones

Overdose & Brands

Symptoms of Flocatafenine overdose includes:

  • slow/shallow breathing
  • severe stomach pain
  • and vomit that look like coffee grounds
  • black/bloody stools
  • extreme drowsiness

If you think you may have used Floctafenine more than the usual recommended dose, seek medical help immediately.

 

Available Brand:

  • Attentil

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