Raltitrexed is a drug that belongs to a class of medicines known as antimetabolites. It is used to treat colorectal cancer and is a folate analogue. It inhibits DNA synthesis and leads to cell death by being a thymidylate synthase (TS) potent inhibitor.
Raltitrexed is for the palliative treatment of advanced colorectal cancer.
Raltitrexed should not be given to people who have severe kidney disease, women who are pregnant and women who are breastfeeding.
Raltitrexed may give rise to the following side effects:
Precautions
Take caution in those with the following conditions:
Interactions
Raltitrexed may interact with the following medicines:
Symptoms of overdose include haematological and gastrointestinal toxicity.
Seek medical help immediately.
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