Tocilizumab is an interleukin-6 (IL-6) receptor blocker that works by blocking a substance (IL-6) in the body that contributes to inflammation.
Tocilizumab is an interleukin-6 (IL-6) receptor blocker that works by blocking a substance (IL-6) in the body that contributes to inflammation.
This medication is used to treat moderate to severe rheumatoid arthritis (RA) in certain patients. It may be used alone or in combination with other medicine. It may also be used for other conditions as determined by your doctor.
Tocilizumab increases the risk of developing serious and sometimes fatal infections, including tuberculosis (TB), fungal infection, and other types of infection. Most patients who developed these infections were also taking medicine that suppressed their immune system (eg, Corticosteroids, Methotrexate).
Individuals with active infections should not be treated with tocilizumab. Tocilizumab may worsen or cause new diseases of the nervous system.
The most common adverse effects of Tocilizumab may include:
Use of tocilizumab has been associated with serious infections such as:
Other side effects include:
Precautions
Some medical conditions may interact with this drug. Tell your doctor or pharmacist if you have any medical conditions, especially if:
Interactions
Some medicines may interact with tocilizumab. Tell your healthcare provider if you are taking any other medicines, especially any of the following:
-The risk of serious infection may be increased
–The risk of liver side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the liver
–The risk of severe stomach or bowel problems may be increased
-Their effectiveness may be decreased by tocilizumab
Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.
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