PERAMPANEL

Perampanel is an anticonvulsant that works by slowing abnormal nerve impulses in the brain.

Uses

This medication is used in combination with other medications to treat certain types of seizures in people who are 12 years of age or older.

Warnings

Do not use Perampanel if:

You are allergic to any ingredient in Perampanel
You have severe liver or kidney problems, or you are on dialysis
You are taking rifampin or St. John’s wort

If any of these apply to you, contact your doctor or health care provider right away.

Side Effects

Side effects of this medication include:

Dizziness or a sense of spinning
Drowsiness
Constipation
Nausea
Vomiting
Weight gain
Irritability
Weakness
Problems with coordination
Muscle or joint pain
Blurred or double vision

If any of these apply to you, contact your doctor or health care provider right away.

Precautions

Precautions

Before using Perampanel, tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

If you are pregnant, planning to become pregnant, or are breast-feeding
If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
If you have allergies to medicines, foods, or other substances
if you have a history of liver or kidney problems
If you have a history of mental or mood problems (eg, depression), behavior problems (eg, aggression, hostility), suicidal thoughts or actions, or alcohol or other substance abuse or dependence
If you take other medicine for seizures

Interactions

Drug interactions may interfere with how your medication works. Tell your health care provider if you are taking any other medicines, especially any of the following:

Carbamazepine, hydantoins (eg, phenytoin), oxcarbazepine, phenobarbital, primidone, rifampin, or St. John’s wort because they may decrease Perampanel’s effectiveness
Hormonal Birth Control (eg, birth control pills) because their effectiveness may be decreased by Perampanel

Overdose & Brands

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing. Symptoms of overdose may include the following:

Dizziness
Unusual changes in behavior or mood
Agitation
Aggressive behavior

Available brands:

Fycompa