Tell your doctor or pharmacist promptly if any of these effects persist or worsen:
- Drowsiness
- Dizziness
- Constipation
- dry mouth
- weight gain
- blurred vision
This drug may cause muscle/nervous system problems (extrapyramidal symptoms-EPS). Therefore, tell your doctor right away if you notice any of the following side effects:
- stiff muscles
- restlessness/constant need to move
- shaking (tremor)
- slow/shuffling walk
- drooling/trouble swallowing
- mask-like expression of the face
- severe muscle spasms/cramping (such as twisting neck, arching back, eyes rolling up)
Tell your doctor right away if you have any serious side effects, including:
- easy bruising/bleeding
- fainting
- depression/suicidal thoughts
- difficulty urinating
- signs of infection (such as fever, persistent sore throat)
- seizures
- severe stomach/abdominal pain
This medication may cause a condition known as tardive dyskinesia. Tell your doctor right away if you develop any involuntary/repetitive muscle movements such as lip smacking/puckering, tongue thrusting, chewing, or finger/toe movements.
For females, increase in prolactin due to loxapine may result in unwanted breast milk, missed/stopped periods, or difficulty becoming pregnant. For males, it may result in decreased sexual ability, inability to produce sperm, or enlarged breasts. These are rare cases that may occur.
This medication may rarely cause a very serious condition called neuroleptic malignant syndrome (NMS). Get medical help right away if you have any of the following symptoms:
- Fever
- muscle stiffness/pain/tenderness/weakness
- severe tiredness
- severe confusion
- sweating
- fast/irregular heartbeat
- dark urine
- change in the amount of urine
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:
- Rash
- itching/swelling (especially of the face/tongue/throat)
- severe dizziness
- trouble breathing
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.