Quinapril belongs to a group of medicines called angiotensin converting enzyme (ACE) inhibitors, which help relax blood vessels. ACE inhibitors prevent an enzyme in your body from producing angiotensin II, a substance in your body that narrows your blood vessels and releases hormones that can raise your blood pressure. This narrowing can cause high blood pressure and force your heart to work harder.
Used to lower high blood pressure (hypertension). It is also used to treat heart failure.
Do not give quinapril to pregnant women and persons with history of angioedema related to previous ACE inhibitor treatment. Angioedema is the rapid edema, or swelling, of the area beneath the skin or mucosa. It is normally an allergic reaction, but can also be hereditary. Do not give to patients with diabetes and kidney impairment who are taking the anti-hypertension drug, aliskiren.
Dizziness, lightheadedness, or tiredness may occur as your body adjusts to the medication. Dry cough, nausea, or vomiting may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Precautions
Before taking quinapril, tell your doctor or pharmacist if you are allergic to it; or to other ACE inhibitors (such as benazepril); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Interactions
Some products that may interact with this drug include: aliskiren, certain drugs that weaken the immune system/increase the risk of infection (such as everolimus, sirolimus), lithium, drugs that may increase the level of potassium in the blood (such as ARBs including losartan/valsartan, birth control pills containing drospirenone), sacubitril.
Symptoms of overdose may include: severe dizziness, fainting. If overdose is suspected, bring the victim to the nearest hospital immediately.
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