Precautions
- Inform your doctor
- Allergy to the medication or any allergies
- Medical History of fungal infection in your blood (e.g., candidiasis, valley fever), bleeding problems, blood clots, brittle bones (osteoporosis), diabetes, eye problems (e.g., cataracts, glaucoma, infection of the eye), heart problems (e.g., congestive heart failure), high blood pressure, infections (e.g., herpes, tuberculosis), kidney disease, liver disease (e.g., cirrhosis), mental/mood disorders (e.g., anxiety, depression, psychosis), low blood minerals (e.g., calcium, potassium), stomach/intestinal problems (e.g., diverticulitis, peptic ulcer disease, ulcerative colitis), seizures, thyroid problems.
- Signs of infection may be masked therefore any injuires or signs of infection must be reported such as persistent sore throat/fever/cough, pain while urinating, skin sores) that occur during treatment.
- Do not receive any vaccines during or after treatment with fludarabine. Consult with your physician before receiving any vaccine.
- Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received oral polio vaccine or flu vaccine inhaled through the nose.
- Exposure to chickenpox or measles infection must be avioded while taking this medication unless you have previously had these infections (e.g., in childhood). If exposure is suspected, seek immediate medical attention.
- Limit alcoholic beverages while taking this medication to lower the risk of stomach/intestinal bleeding.
- This medication may slow down a child’s growth with prolonged use. Consult uour physician for more details.
- Should only be used when there is a clear need during pregnancy as it may harm an unborn baby. If you are planning to be pregnant or think you may be pregnant, discuss the risks and benefits of use with your doctor.
- Consult your doctor before breast-feeding as this medication passes into breast milk and may cause unwanted effects on your baby
Interactions
Taking multiple drugs may affect how medications work and/or cause unwanted side effects. List down all the medications you are taking and inform your physician and pharmacist. Do not take, discontinue, or alter any dose of medications without prior approval of your physician.
- Products that may interact with this medication include:
- aldesleukin
- digoxin
- drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel
- “blood thinners” such as dabigatran/warfarin
- NSAIDs such as aspirin/celecoxib/ibuprofen)
- hormones (e.g., androgens, birth control pills, estrogens)
- immunosuppressants (e.g., cyclosporine)
- mifepristone
- vaccines
- drugs affecting liver enzymes that remove fludrocortisone from your body (e.g., rifamycins such as rifampin/rifabutin, certain anti-seizure medicines such as barbituates/phenytoin).
If your doctor prescribed you low dose aspirin, continue to take it unless you are told otherwise