COMMON BRAND NAME(S): Dipentum
GENERIC NAME(S): OLSALAZINE SODIUM
Description: Olsalazine is a 5-aminosalicylic acid derivative which has anti-inflammatory properties. Pharmacokinetics:
Absorption: <3%; very little intact olsalazine is systemically absorbed. Time to peak: approx 1 hr.
Distribution: Protein binding, plasma: >99%.
Metabolism: Primarily via colonic bacteria to active drug.
Excretion: Half-life elimination: 56 min; primarily faeces.