Saxagliptin + Metformin is a combination drug that is composed of the diabetes drugs Saxagliptin and Metformin.
Saxagliptin is a drug that is used to treat Type 2 diabetes mellitus. It inhibits the enzyme dipeptidylpeptidase-4 (DPP-4) which inactivates incretin hormones. This results to an increase in incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)]. These hormones control glucose homeostasis by increasing insulin from pancreatic beta-cells and diminishing glucagon from pancreatic alpha-cells, thus decreasing glucose production in the liver.
Metformin is a biguanide drug that lessens glucose production in the liver by diminishing gluconeogenesis and glycogenolysis, diminishes intestinal absorption of glucose, and improves insulin sensitivity by enhancing take-up of glucose in the tissues.
Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.
The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.
If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.
Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.
If you have any inquiries with regards to information, ask your physician or pharmacist.